General Surgery

A common mutation in the KRAS gene is associated with improved overall survival in pancreatic ductal adenocarcinoma (PDAC) compared with other variants, in part because the mutation appears to lead to less invasiveness and weaker biological activity, according to a multicenter study conducted at Weill Cornell Medicine, Memorial Sloan Kettering, and other institutions.

Researchers from Weill Cornell Medicine have used a cutting-edge model system to uncover the mechanism by which SARS-CoV-2, the virus that causes COVID-19, induces new cases of diabetes, and worsens complications in people who already have it.

Using state-of-the-art tissue engineering techniques and a 3D printer, researchers at Weill Cornell Medicine and Cornell Engineering have assembled a replica of an adult human ear that looks and feels natural.

A drug screening system that models cancers using lab-grown tissues called organoids has helped uncover a promising target for future pancreatic cancer treatments, according to a new study from researchers at Weill Cornell Medicine.

A drug currently in clinical trials as a cancer therapy can also stimulate pancreatic beta cells to secrete insulin, revealing a previously unknown mechanism for insulin regulation in type 2 diabetes, according to a new study by Weill Cornell Medicine investigators.

In experiments of unprecedented scale, investigators at Weill Cornell Medicine and the National Institutes of Health have revealed new aspects of the complex genetics behind Type 2 diabetes.

Sara Mathew, associate director of research and operations administration in the Department of Surgery at Weill Cornell Medicine, has been selected as one of Crain’s Notable Leaders in Health Care.

Weill Cornell Medical College student Pauline Flaum-Dunoyer is a natural storyteller and historian.

A United States Food and Drug Administration mandate to limit the dosage of acetaminophen in pills that combine acetaminophen and opioid medications is significantly associated with subsequent reductions in serious liver injury.

A mitochondrial gene plays a crucial role in genetic susceptibility to Zika, Dengue, and SARS-CoV-2 infections, a study by Weill Cornell Medicine investigators showed.

SARS-CoV-2 infections of women in late pregnancy frequently spread to their placentas and led to inflammation.

A tool to evaluate potential transplant candidates that looks at tumor marker levels in the blood can help predict which liver cancer patients are most likely to have their disease remain under control after receiving a transplant, according to a new study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian.

Two gene variants found in African American women may explain why they are more likely to be diagnosed with triple negative breast cancer (TNBC) than white women of European ancestry, according to Weill Cornell Medicine and NewYork-Presbyterian investigators.

SARS-CoV-2, the virus causing the global COVID-19 pandemic, can infect human pancreatic cells and alter their physiology.

The heart damage seen in many severely ill COVID-19 patients results in part from infection-activated immune cells called macrophages, which infiltrate the heart and secrete cell-damaging chemicals, according to a study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian, Icahn School of Medicine at Mount Sinai and Columbia University Irving Medical Center.

In early March, Dr. Shetal Shah, MD ’00, was in Albany along with other doctors to lobby for important regulations to protect children’s health. As president of New York State Chapter 2 of the American Academy of Pediatrics, Dr. Shah had been there many times before, including last summer as the state grappled with the largest measles outbreak in decades.