Obstetrics and Gynecology

Vaccinating mothers against respiratory syncytial virus (RSV) during late pregnancy to protect their newborns is not associated with an increased risk of preterm birth or other poor outcomes, according to a study by Weill Cornell Medicine and NewYork-Presbyterian investigators.

By teasing out the biological mechanisms underlying postpartum mental health disorders, investigators at Weill Cornell Medicine are laying the groundwork for new ways to detect and treat women at risk. 

Researchers find that including BRCA1 testing at the time of obstetrical prenatal carrier screening may be a cost-effective way to identify those at risk of certain cancers.

When Nila Charles was diagnosed with breast cancer, she was the mother of two young children, working long hours and caring for a family member who was also diagnosed with cancer.

Dr. Jeannine Gerhardt, an assistant professor of stem cell biology in obstetrics and gynecology and in reproductive medicine at Weill Cornell Medicine, has received a five-year, $2.1 million grant from the National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health, for the study of repetitive DNA and RNA sequences and the mechanisms by which they cause cell dysfunction and diseases.

Weill Cornell Medicine has been awarded a five-year, $5 million grant from the United States Department of Health and Human Services through the Office of Population Affairs under the Teen Pregnancy Prevention Program to conduct a randomized trial testing whether a bilingual video game called “No Baby No (No Bebé No)” can increase the use of contraception among sexually active Black and Hispanic adolescents.

Pregnant individuals who had a previous COVID-19 infection and received a full course of COVID-19 vaccination and a booster have the strongest immune protection from the disease – and pass that protection along to their unborn babies.

The program has prepared Weill Cornell Medicine faculty members to grow into institutional leaders. 

Weill Cornell Medical College student Pauline Flaum-Dunoyer is a natural storyteller and historian.

The immune system of pregnant women with anxiety is biologically different from that of pregnant women without anxiety.

A protein commonly found at high levels in lung cancer cells controls a major immunosuppressive pathway that allows lung tumors to evade immune attack.

An artificial intelligence algorithm can determine non-invasively, with about 70 percent accuracy, if an in vitro fertilized embryo has a normal or abnormal number of chromosomes.

The long-term immune response to SARS-CoV-2 mRNA vaccination was similar in pregnant individuals compared with non-pregnant individuals of reproductive age.

Error-prone DNA replication and repair may lead to mutations and cancer in individuals who inherit a mutant copy of the BRCA1 gene, according to a new study by Weill Cornell Medicine investigators.

A typical gut bacterium that can spread through the body and cause a serious infection resists natural immune defenses and antibiotics by enhancing its protective outer layer, known as the cell envelope, according to a new study by Weill Cornell Medicine investigators. 

A cellular process known as autophagy that helps rid cells of debris may be impaired in pregnant women who go on to develop post-partum depression (PPD), according to new research from Weill Cornell Medicine, Johns Hopkins University School of Medicine and UVA Health investigators.

Hysteroscopic sterilization, a nonincisional procedure, was found to be as effective as minimally invasive laparoscopic sterilization in preventing pregnancy, but both methods had higher than expected failure rates, according to a new study led by an investigator at Weill Cornell Medicine.

High levels of anti-Mullerian hormone (AMH) have traditionally been thought of as merely a passive byproduct of polycystic ovary syndrome (PCOS), but a new preclinical study by Weill Cornell Medicine researchers suggests that the hormone plays an active role in the disorder and may contribute to problems with ovulation and fertility.

A protein that masterminds the way DNA is wrapped within chromosomes has a major role in the healthy functioning of blood stem cells, which produce all blood cells in the body, according to a new study from researchers at Weill Cornell Medicine.

COVID-19 vaccination of expectant mothers elicits levels of antibodies to the SARS-CoV-2 outer “spike” protein at the time of delivery that don’t vary dramatically with the timing of vaccination during pregnancy and thus don’t justify delaying vaccination, according to a study from researchers at Weill Cornell Medicine and NewYork-Presbyterian.