Research

Gene mutations that are thought to be very early events in the development of leukemias and other blood disorders appear to set the stage for malignancy by increasing the production of certain types of blood cells at the expense of others.

Ion channels, which allow potassium and sodium ions to flow in and out of cells, are crucial in neuronal ‘firing’...

The fourth annual NYC Health Hackathon brought together students and faculty members from Weill Cornell Medicine, Cornell’s Ithaca campus and several local and national academic institutions, to develop high-tech healthcare innovations. 

Winner of a prestigious fellowship for postdocs, Dr. Adrian Jinich aims to spur health in developing countries—and inspire the next generation of STEM students.

Preclinical work suggests the targeted drug palbociclib may boost the effectiveness of chemotherapy in pancreatic cancer if the two treatments are given in the right sequence.

Urinary tract infections (UTIs) in kidney transplant patients may be caused by bacteria that originate in the digestive tract, according to investigators at Weill Cornell Medicine, Cornell University and NewYork-Presbyterian.

Scientists at Weill Cornell Medicine, Stanford University and the University of California, San Francisco have adapted genome editing tools to function in a common species of intestinal bacteria. 

Gut microbes influence blood glucose levels by acting directly on the liver, not by regulating the energy expenditure of specialized fat tissues, which use glucose as fuel to create heat.

Weill Cornell Medicine, in collaboration with the Moffitt Cancer Center in Tampa, Florida and the Universidade de São Paulo in Brazil, has been awarded a five-year, $8.3 million grant from the National Cancer Institute to investigate ways to prevent human papillomavirus (HPV)-related cancers in people living with human immunodeficiency virus (HIV) infection.

A common variation in a human gene that affects the brain’s reward processing circuit increases vulnerability to the rewarding effects of the main psychoactive ingredient of cannabis in adolescent females, but not males.

The scope of the DNA changes that drive cancers has been illuminated as never before in a set of studies by a large international scientific team including Weill Cornell Medicine researchers. In six studies published Feb. 5 in Nature, and 18 papers in other Nature-affiliated journals, this scientific consortium reported the results from analyses of DNA from more than 2,600 biopsied tumor samples across 38 different types of cancer. 

An underlying problem with the production of important cellular building blocks called sphingolipids may explain why children with certain genetic risk factors develop asthma.

Immune cell activity in the brain differs between males and females in ways that may explain why some neurodegenerative diseases affect the sexes differently

Does a toxin found in the Arabian Desert Raise the Risk of Neurodegenerative Diseases Like ALS

Molecules that coordinate the development of highly specialized blood vessels in the kidney have been identified by investigators at Weill Cornell Medicine, University of Texas Southwestern Medical Center and Hofstra University. The findings pave the way toward new strategies for repairing damaged organs.

When Cornell President Martha E. Pollack talks about the experiences that shaped her career, she starts by talking about mentorship, and a pivotal conversation she had with Professor Hoyt Alverson at Dartmouth College.

An inexpensive program using trained community members to deliver a structured program based on cognitive behavioral therapy by telephone was able to improve daily functioning, self-reported physical activity, and overall quality of life among diabetic patients with chronic pain.

In an IVF breakthrough, artificial intelligence helps identify the embryos most likely to lead to successful pregnancies.

Trainees of Hispanic ethnicity, compared with non-Hispanic trainees, were only about 40 percent as likely to pass, on the first try, the final examination for American Board of Surgery (ABS) certification, despite having passed an initial qualifying exam to demonstrate sufficient applied knowledge, according to a study led by Weill Cornell Medicine and NewYork-Presbyterian investigators. 

An eight-week course of treatment with the daily oral drug glecaprevir/pibrentasvir cured chronic hepatitis C virus (HCV) infection in 98% of previously untreated patients with an asymptomatic form of cirrhosis or liver scarring known as compensated cirrhosis.