Research

Does a toxin found in the Arabian Desert Raise the Risk of Neurodegenerative Diseases Like ALS

Molecules that coordinate the development of highly specialized blood vessels in the kidney have been identified by investigators at Weill Cornell Medicine, University of Texas Southwestern Medical Center and Hofstra University. The findings pave the way toward new strategies for repairing damaged organs.

When Cornell President Martha E. Pollack talks about the experiences that shaped her career, she starts by talking about mentorship, and a pivotal conversation she had with Professor Hoyt Alverson at Dartmouth College.

An inexpensive program using trained community members to deliver a structured program based on cognitive behavioral therapy by telephone was able to improve daily functioning, self-reported physical activity, and overall quality of life among diabetic patients with chronic pain.

In an IVF breakthrough, artificial intelligence helps identify the embryos most likely to lead to successful pregnancies.

Trainees of Hispanic ethnicity, compared with non-Hispanic trainees, were only about 40 percent as likely to pass, on the first try, the final examination for American Board of Surgery (ABS) certification, despite having passed an initial qualifying exam to demonstrate sufficient applied knowledge, according to a study led by Weill Cornell Medicine and NewYork-Presbyterian investigators. 

An eight-week course of treatment with the daily oral drug glecaprevir/pibrentasvir cured chronic hepatitis C virus (HCV) infection in 98% of previously untreated patients with an asymptomatic form of cirrhosis or liver scarring known as compensated cirrhosis.

Decreased amounts of a neurotransmitter called GABA, whose main function is to reduce activity in the brain, leads to changes in the number of neurons in the developing brain and alters signaling between them.

Weill Cornell Medicine scientists have built the first global database of clinical trials testing a rapidly expanding approach to cancer treatment that involves genetically modifying immune cells to recognize specific targets on a patient’s cancer cells and attack them.

Weill Cornell Medicine scientists have developed a machine-learning algorithm capable of predicting biological targets of prospective drug molecules.

Medical schools evaluating the merits of eliminating tuition, as opposed to pursuing debt-free initiatives, should approach the debate in the same way physicians and scientists engage in medicine: with empirical data, according to new commentary by leaders at Weill Cornell Medicine.

Scientists at Weill Cornell Medicine have discovered how a key transcription factor protein called KLF4 helps “reprogram” skin cells into stem cells, according to a new study.

African American patients who underwent knee-replacement surgery were several times more likely than white patients of similar age to be discharged to inpatient facilities for post-operative care and rehabilitation rather than home, according to a large study from a team led by Weill Cornell Medicine investigators. 

Weill Cornell Medicine and the University of Virginia School of Medicine have received a grant from the National Heart, Lung, and Blood Institute and Three Lakes Partners, a philanthropic family organization, to fund the first precision medicine research initiative aiming to transform the diagnosis and treatment of interstitial lung diseases, particularly idiopathic pulmonary fibrosis.

Neurons have a special mechanism that allows them to quickly boost energy production to support bursts of brain activity, according to a new study from scientists at Weill Cornell Medicine.

A new technology developed by Weill Cornell Medicine and Max Planck Institute for Medical Research scientists allows the controlled, on-and-off “switching” of neural receptors with unprecedented efficiency and precision. 

A change in the protein composition of chromatin—the condensed, packaged form of DNA in the nucleus—boosts the expression of metastasis-related genes; blocking this change appears to stop tumor cells from forming new tumors in mice, suggests a study by Weill Cornell Medicine investigators. 

Weill Cornell Medicine has been awarded a grant from the National Institute on Disability, Independent Living, and Rehabilitation Research to create a center aimed at developing technology to help older adults who have cognitive impairments (CIs).

The gene mutation that underlies a puzzling disorder featuring skin, brain and other abnormalities has been discovered by a team of scientists from Weill Cornell Medicine and the Fédération Hospitalo-Universitaire TRANSLAD (FHU-TRANSLAD) in France.

Dr. Costantino Iadecola, director of the Feil Family Brain and Mind Research Institute and the Anne Parrish Titzell Professor of Neurology at Weill Cornell Medicine, has been recognized as a 2019 Distinguished Scientist by the American Heart Association for his outstanding contributions to cardiovascular, stroke and dementia research.