Research

A high-fat diet increases prostate cancer tumor progression in mice by mimicking the effects of a cancer-promoting gene and may contribute to more aggressive cancer in humans, according to a study from Weill Cornell Medicine and Dana-Farber Cancer Institute investigators.

The protein adipsin, which is produced in body fat, helps protect insulin-secreting cells called pancreatic beta cells from destruction in type 2 diabetes, according to a new study by researchers at Weill Cornell Medicine and NewYork-Presbyterian. 

A protein that breast, lung and other cancers use to promote their spread—or metastasis—to the brain, has been identified by a team led by Weill Cornell Medicine and New York-Presbyterian investigators. The protein, CEMIP, will now be a focus of efforts to predict, prevent and treat brain metastases, which are a frequent cause of cancer deaths.

Personalized medical interventions to improve cardiovascular, metabolic and other modifiable risk factors for Alzheimer’s disease may improve cognitive function, according to a study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian. 

For patients with a genetic syndrome that predisposes them to many cancers, a new vaccine could be a lifesaver

New cellular and molecular processes underlying communication between gut microbes and brain cells have been described for the first time by scientists at Weill Cornell Medicine and Cornell’s Ithaca campus.

A set of powerful laboratory and computational techniques developed by scientists at Weill Cornell Medicine, the New York Genome Center (NYGC) and the Broad Institute will enable investigators to map the capacity of tumors to develop resistance to drugs and drug combinations. 

A high-salt diet may negatively affect cognitive function by causing a deficiency of the compound nitric oxide, which is vital for maintaining vascular health in the brain, according to a new study in mice from Weill Cornell Medicine researchers. 

In the roughly 100 years since Alois Alzheimer first described the devastating neurodegenerative disease that now bears his name, scientists have developed an increasingly sophisticated understanding of the brain. 

Dr. Hagen Tilgner is exploring how faulty building instructions for brain cells may give rise to depression, schizophrenia, Alzheimer’s disease and more

Dr. Samie R. Jaffrey, the Greenberg-Starr Professor of Pharmacology at Weill Cornell Medicine, has been awarded a Maximizing Investigators’ Research Award (MIRA) from the National Institute of Neurological Disorders and Stroke (NINDS).

Weill Cornell Medicine scientists have built the first 3-D-printed automated synthesis units (ASUs) for producing customized radioactive drugs.

Researchers in Doha and New York are collaborating to explore the Qatari genome.

Dr. Peter Goldstein, a professor of anesthesiology at Weill Cornell Medicine, has been awarded a grant from the National Institutes of Health  for a project to develop a non-opioid, non-addicting medicine for a hard-to-treat form of pain called neuropathic pain.

Dr. Chun-Jun (“C.J.”) Guo has won a Director’s New Innovator Award from the National Institutes of Health for an ambitious project to detail how the hundreds of different bacterial species living in the human gut contribute to human health and disease.

Dr. Simon Scheuring, a professor of physiology and biophysics in anesthesiology at Weill Cornell Medicine has been awarded a prestigious National Institutes of Health Director’s Pioneer Award for a project aimed at solving long-standing mysteries about the structural workings of important proteins.

A set of definitions for distinguishing the severity of bleeding in critically ill children has been developed by a team led by researchers at Weill Cornell Medicine and NewYork-Presbyterian.

After extensive data gathering and analysis—plus a worldwide media Frenzy—NASA’s famed Twins Study has begun to yield results.

A novel mechanism that regulates activity in the brain, discovered by Weill Cornell Medicine investigators, may help explain the origins of one common type of dementia.

Cornell Tech and Weill Cornell Medicine have been awarded a Robert Wood Johnson Foundation (RWJF) grant that will fund interdisciplinary research on the role of technology among home health aides caring for adults with heart failure.