Feil Family Brain and Mind Research Institute

Weill Cornell Medicine scientists have built the first global database of clinical trials testing a rapidly expanding approach to cancer treatment that involves genetically modifying immune cells to recognize specific targets on a patient’s cancer cells and attack them.

Dr. Costantino Iadecola, director of the Feil Family Brain and Mind Research Institute and the Anne Parrish Titzell Professor of Neurology at Weill Cornell Medicine, has been recognized as a 2019 Distinguished Scientist by the American Heart Association for his outstanding contributions to cardiovascular, stroke and dementia research.

A high-salt diet may negatively affect cognitive function by causing a deficiency of the compound nitric oxide, which is vital for maintaining vascular health in the brain, according to a new study in mice from Weill Cornell Medicine researchers. 

In the roughly 100 years since Alois Alzheimer first described the devastating neurodegenerative disease that now bears his name, scientists have developed an increasingly sophisticated understanding of the brain. 

Dr. Hagen Tilgner is exploring how faulty building instructions for brain cells may give rise to depression, schizophrenia, Alzheimer’s disease and more

A novel mechanism that regulates activity in the brain, discovered by Weill Cornell Medicine investigators, may help explain the origins of one common type of dementia.

Early disruptions in brain cell activity may give rise to autism.

While heart attacks that cause classic symptoms such as pressure and pain in the chest are an established risk factor for stroke because they can lead to blood clot formation, new research by Weill Cornell Medicine and NewYork-Presbyterian investigators indicates that heart attacks that have few, if any, recognized symptoms may also increase risk.

The chemical element selenium, an essential nutrient for humans and other animals, protects the brain after a stroke and may be a basis for future stroke therapies, according to a study from scientists at Burke Neurological Institute and Weill Cornell Medicine.

Weill Cornell Medicine has experienced dynamic growth in its research enterprise over the past five years, an achievement that underscores the institution’s mission to provide patients with the most advanced treatments and therapies.

Long-term spaceflight causes more changes to gene expression than shorter trips, especially to the immune system and DNA repair systems, according to research by Weill Cornell Medicine and NASA investigators as part of NASA’s Twins Study, which followed the only set of identical twin astronauts for more than two years.  

The powerful but temporary benefits of ketamine against depression might be extended if the new brain-cell connections it promotes could be preserved, according to a new study.

Older adults with cancer are nearly 70 percent more likely to suffer a stroke or heart attack in the year prior to their diagnosis compared with peers without a cancer diagnosis in that same time period, according to new research by Weill Cornell Medicine, NewYork-Presbyterian and Memorial Sloan Kettering Cancer Center investigators.

Measuring brain activity in response to hearing a brief narrative can identify patients with severe brain injury who have preserved high-level cognition despite showing limited or no consciousness at the bedside, according to a study by Weill Cornell Medicine researchers.

A protein linked to both Alzheimer’s disease and a form of dementia increases the risk of cognitive impairment by reducing the number and responsiveness of blood vessels in the organ.

Sensory stimulation during a critical period soon after birth is essential for establishing networks in the brain...

A high-salt diet reduces resting blood flow to the brain and causes dementia in mice, according to a new study by scientists from Weill Cornell Medicine.

Young people with a history of strokes caused by blood clots should be evaluated for a congenital condition characterized by a hole in the heart. If present, surgical closure should be considered to prevent future stroke, according to an editorial by a Weill Cornell Medicine and NewYork-Presbyterian neurologist.

The goal of the Dean’s Inaugural Symposium on Opportunities for Entrepreneurship and Academic Drug Development, hosted at Weill Cornell Medicine’s Uris Auditorium, was to highlight the resources available to investigators to help them turn their research findings into new treatments and therapies for patients.

ARCADIA, a multicenter phase III trial, will study the role of abnormalities in the structure and function of the heart’s left atrium, or atrial cardiopathy, in stroke patients, and test a medication that could prevent them from experiencing recurrent strokes.