News from WCM

Women with severe coronary heart disease causing narrowing or blockages in the arteries may derive greater long-term benefits from coronary artery bypass grafting compared with percutaneous coronary intervention, also known as stenting, according to a large study by Weill Cornell Medicine investigators.

Weill Cornell Medicine is poised to thrive in the coming years, with a planned expansion of its clinical enterprise serving as an engine for overall institutional growth, Dean Robert Harrington conveyed Dec. 16 during his biannual State of Weill Cornell Medicine address.

While many women assume pelvic floor health issues are simply their fate—part of having vaginal deliveries, getting older, gaining weight or entering menopause, they are not a part of normal aging. Dr. Larissa Rodríguez is working to change perceptions of this disorder, which affects one-in-three women in her lifetime.

Dr. John Blenis's lab discovered that low levels of folate, a B vitamin essential for cell growth, can trigger specific genetic changes found in lung tumors, establishing a link between nutrition and cancer, which may open new dietary approaches for prevention and treatment.

Three minutes and one slide were all it took for twelve young scientists to turn cutting-edge research into dramatic stories of hope at Weill Cornell Medicine’s tenth annual Three-Minute Thesis (3MT) competition on Nov. 13 in Uris Auditorium.

Dr. Hazel Szeto's discovery of a first-in-class compound that had mitochondrial therapeutic potential is now a U.S. Food and Drug Administration-approved drug.

Dr. Despina Siolas, assistant professor of medicine at Weill Cornell Medicine, is working to personalize treatment for pancreatic cancer and develop new therapeutic regimens that save more patient lives.

Weill Cornell Medicine’s Ninth Annual Dean’s Symposium on Innovation and Entrepreneurship celebrated and fostered the entrepreneurial spirit on Nov. 17 at Weill Cornell's Griffis Faculty Club.

Dopamine neurons in a part of the brain called the midbrain may, with aging, be increasingly susceptible to a vicious spiral of decline driven by fuel shortages, according to a study led by Weill Cornell Medicine investigators.

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by Weill Cornell Medicine investigators.

The roots of addiction risk may lie in how young brains function long before substance use begins, according to a new study from Weill Cornell Medicine.

Chemotherapy activates a stress sensor in immune cells, triggering inflammation and nerve damage, which may help explain why many cancer patients experience debilitating pain as a side effect, according to a new study by Weill Cornell Medicine and Wake Forest University School of Medicine researchers.

A new study has discovered a molecular signal that tumors exploit to exhaust the T cells meant to destroy them—and how silencing that signal could revive the body’s immunity.

Hypertension impairs blood vessels, neurons and white matter in the brain well before the condition causes a measurable rise in blood pressure, according to a new preclinical study from Weill Cornell Medicine investigators.

Gut microbes may play a key role in training a mother’s immune system to adapt to the developing fetus during pregnancy, according to a preclinical study by Weill Cornell Medicine investigators.

Prior exposure to coronaviruses that cause ordinary colds can boost the immune system’s ability to attack a vulnerable site on the COVID-19-causing coronavirus SARS-CoV-2, according to a study led by investigators at Weill Cornell Medicine.

A Weill Cornell Medicine investigator and other members of a technical advisory group to the World Health Organization and United Nations Children’s Fund have outlined measures that nations can take to ensure that children’s health is accounted for within climate change goals. 

As Medicaid funding cuts enacted through the One Big Beautiful Bill Act are expected to reduce health coverage among adults, researchers and clinicians warn that children are at increasing risk of unintended downstream effects.

Weill Cornell Medicine investigators have identified an early step in a cellular process that leads to inflammation in fat cells and may result in type 2 diabetes in people with obesity.

A team led by Weill Cornell Medicine and University of Miami’s Miller School of Medicine investigators has been awarded a five-year, $4 million grant from the National Institute on Drug Abuse (NIDA) for health economics research.