Biochemistry

Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies by Weill Cornell Medicine investigators.  

SARS-CoV-2 infections of women in late pregnancy frequently spread to their placentas and led to inflammation.

The SARS-CoV-2 virus can infect specialized pacemaker cells that maintain the heart’s rhythmic beat, setting off a self-destruction process within the cells, according to a preclinical study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and NYU Grossman School of Medicine.

Tumors can use an enzyme called ART1 to thwart antitumor immune cells, making the enzyme a promising new target...

Pound for pound, the brain consumes vastly more energy than other organs, and, puzzlingly, it remains a fuel-guzzler even when its neurons are not firing signals called neurotransmitters to each other. Now researchers at Weill Cornell Medicine have found that the process of packaging neurotransmitters may be responsible for this energy drain.

Researchers at Weill Cornell Medicine have shown that they can record the high-speed motions of proteins while correlating their motion to function.

Endocrinology Chief Dr. Laura Alonso—A specialist in diabetes research and treatment—is exploring ways to restore the body’s insulin production

The study of human pluripotent stem cells, which can develop into any cell type in the body, is providing Weill Cornell Medicine and NewYork-Presbyterian investigators with new insights into the virus that causes COVID-19 and how it may infect organs such as the pancreas and liver.

A new technology developed by Weill Cornell Medicine and Max Planck Institute for Medical Research scientists allows the controlled, on-and-off “switching” of neural receptors with unprecedented efficiency and precision. 

An enzyme found in brain cells can break apart the precursors to plaques that accumulate in the organ and cause toxicity in Alzheimer’s disease, according to a new study led by Weill Cornell Medicine scientists.

Dr. Ghazaleh Ashrafi, a postdoctoral associate in biochemistry at Weill Cornell Medicine, has won a 2017 Tri-Institutional Breakout Award for Junior Investigators.

A tiny tubular structure directly controls synapses, the junctions through which communication signals flow between nerve cells.

New research provides insights into why the brain is so reliant on sugar to function.

The Tri-Institutional Therapeutics Discovery Institute is speeding early-stage drug development through an innovative collaboration between academia and industry.

Dr. Igor Dikiy is the Weill Cornell Graduate School of Medical Sciences' 2015 commencement speaker.

Weill Cornell Medical College and drug maker UCB have teamed up to translate innovative Weill Cornell-led research in bone disorders, metabolic disease and genetics into next-generation treatments.

Researchers at Weill Cornell Medical College have unlocked the structure of a key protein that, when sensing certain viruses and bacteria, triggers the body's immediate immune response.

Luminescent Firefly Protein Used to Study How the Brain Is Fueled NEW YORK (Aug. 9, 2010) — Dr. Timothy Ryan has been selected as one of four scientists to receive the prestigious 2010 McKnight Technological Innovations in Neuroscience Award. The...

The Rab10 Protein Helps Regulate the Uptake of Glucose Into Cells, According to Weill Cornell Medical College Study NEW YORK (April 3, 2007) — Scientists at Weill Cornell Medical College have identified a protein called Rab10 as an important partner...

$2.8 Million Grant Will Further Research into Cellular Transport, with Potential Applications for Wide Range of Diseases NEW YORK (April 14, 2006) — Renowned for his breakthrough discoveries in intracellular trafficking, Weill Medical College of Cornell University biochemist Dr. Frederick...