In Brief

Patients taking an experimental oral GLP-1 drug lost significant weight and improved their heart and metabolic risk factors in a large, international, phase 3 clinical trial led by investigators at Weill Cornell Medicine, McMaster University, York University and other institutions.

Weill Cornell Medicine researchers found that restricting telehealth prescriptions for opioid use disorder could prevent thousands from accessing buprenorphine, a medication that helps people recover from addiction.

A multi-national, multi-institutional study led by Weill Cornell Medicine investigators found little natural resistance to a new HIV therapy called lenacapavir in a population of patients in Uganda.

Weill Cornell Medicine researchers have found that intracranial hemorrhages, or "brain bleeds," caused by a ruptured blood vessel in the brain doubles a person’s risk of developing dementia later in life.

Almost 50 million Americans—disproportionately in rural areas—must drive 25 miles or more to access a gastroenterologist for diagnosis and treatment of issues involving the digestive system, according to a study from Weill Cornell Medicine researchers.

Non-white communities had significantly less access to opioid medications commonly prescribed for moderate to severe pain than white communities over the decade beginning in 2011, according to a study by Weill Cornell Medicine researchers.

The overwhelming majority of those in New York City who obtained a naloxone kit to counteract opioid overdose had a high need for the drug, according to a new study by Weill Cornell Medicine investigators and the New York City Department of Health and Mental Hygiene.

Researchers at Weill Cornell Medicine found that a combination of therapeutic monoclonal antibodies called amubarvimab and romlusevimab did not reduce the occurrence of long COVID symptoms.

Researchers have found that removing protected class regulation from Medicare prescription drug policies could greatly reduce the United States' prescription drug spending—this could have saved potentially $47 billion between 2011-2019.

Researchers at Weill Cornell Medicine have used artificial intelligence to identify drug targets based on mapping regulatory networks in patient tumors.

Weill Cornell Medicine researchers found that female physicians, primary care physicians, psychiatrists and physicians in non-rural areas delivered relatively higher proportions of visits via telehealth. This national analysis may provide key information for policymakers to consider as COVID-19 provisions for expanded Medicare telehealth coverage are set to expire at the end of this year.

Researchers at Weill Cornell Medicine and the epigenetics company TruDiagnostic have uncovered DNA markers associated with retroelements, remnants of ancient viral genetic material, in our genes that act as highly accurate epigenetic clocks predicting chronological age.

The possibility of parental disclosure through online patient portals led older adolescents to hesitate in sharing complete health information with doctors, putting them at risk of missed diagnoses and treatments.

Researchers at Weill Cornell Medicine have discovered in a preclinical model that cytokines, proteins that control immune response, circulating in maternal blood during pregnancy may mitigate an offspring's risk for psychiatric conditions.

Weill Cornell Medicine investigators have uncovered a way to unleash in blood vessels the protective effects of a type of fat-related molecule known as a sphingolipid, suggesting a promising new strategy for the treatment of coronary artery disease.

A new study found that retinoic acid receptors (RARa) in the proximal tubules of the kidney play a crucial role in limiting the damaging effects of kidney injury that often lead to kidney failure.

Male breast cancer has distinct alterations in the tumor genome that may suggest potential treatment targets, according to a study by Weill Cornell Medicine investigators.

A new study identified a set of 140 genes that may help predict enhanced disease-free survival in patients with non-small cell lung cancer (NSCLC) treated with a combination of immunotherapy and low-dose radiation.

The molecular workings of a family of important but hard-to-study proteins called CLCs have been illuminated as never before in a study led by researchers at Weill Cornell Medicine.

The availability of generic antiviral drugs to manage chronic hepatitis B resulted in significant savings to Medicare, despite an increase in prescriptions, according to an analysis by researchers at Weill Cornell Medicine and NewYork-Presbyterian.