In Brief

The first randomized, placebo-controlled clinical trial evaluating the impact of therapeutic monoclonal antibodies on the risk of developing long COVID was led by researchers at Weill Cornell Medicine.

Researchers have found that removing protected class regulation from Medicare prescription drug policies could greatly reduce the United States' prescription drug spending—this could have saved potentially $47 billion between 2011-2019.

Researchers at Weill Cornell Medicine have used artificial intelligence to identify drug targets based on mapping regulatory networks in patient tumors.

Weill Cornell Medicine researchers found that female physicians, primary care physicians, psychiatrists and physicians in non-rural areas delivered relatively higher proportions of visits via telehealth. This national analysis may provide key information for policymakers to consider as COVID-19 provisions for expanded Medicare telehealth coverage are set to expire at the end of this year.

Researchers at Weill Cornell Medicine and the epigenetics company TruDiagnostic have uncovered DNA markers associated with retroelements, remnants of ancient viral genetic material, in our genes that act as highly accurate epigenetic clocks predicting chronological age.

The possibility of parental disclosure through online patient portals led older adolescents to hesitate in sharing complete health information with doctors, putting them at risk of missed diagnoses and treatments.

Researchers at Weill Cornell Medicine have discovered in a preclinical model that cytokines, proteins that control immune response, circulating in maternal blood during pregnancy may mitigate an offspring's risk for psychiatric conditions.

A new study found that retinoic acid receptors (RARa) in the proximal tubules of the kidney play a crucial role in limiting the damaging effects of kidney injury that often lead to kidney failure.

Male breast cancer has distinct alterations in the tumor genome that may suggest potential treatment targets, according to a study by Weill Cornell Medicine investigators.

A new study identified a set of 140 genes that may help predict enhanced disease-free survival in patients with non-small cell lung cancer (NSCLC) treated with a combination of immunotherapy and low-dose radiation.

The molecular workings of a family of important but hard-to-study proteins called CLCs have been illuminated as never before in a study led by researchers at Weill Cornell Medicine.

The availability of generic antiviral drugs to manage chronic hepatitis B resulted in significant savings to Medicare, despite an increase in prescriptions, according to an analysis by researchers at Weill Cornell Medicine and NewYork-Presbyterian.

Cigarette smoking is associated with worse cognitive performance among people 60 years and older, and that association is broadly the same whether or not individuals have hypertension or diabetes.

Vaccination against COVID-19 had no impact on the health of placentas in pregnant women.

Surgery can usually be avoided in children with a rare tumor of the skull, based on new research by investigators from Weill Cornell Medicine, NewYork-Presbyterian, Nicklaus Children’s Hospital, the University of Texas Southwestern, the University of British Columbia and McGovern Medical School.    

A large clinical trial among people living with HIV has found that treating anal precancerous lesions cuts the risk of developing anal cancer by 57 percent compared with active monitoring with no treatment.

New research led by investigators from Weill Cornell Medicine, Fred Hutchinson Cancer Center, University Hospitals Cleveland and Case Western Reserve University found that prostate cancer screening with the prostate specific antigen (PSA) blood test has remarkably favorable tradeoffs.

Growth impairment, a common complication of Crohn’s disease in children, occurs more often in males than females, but the reasons are unclear. Now, a physician-scientist from Weill Cornell Medicine and NewYork-Presbyterian and colleagues at eight other centers have found that factors associated with statural growth differ by sex.

The transition from pre- to post-menopause, with its steep decline in estrogen production, involves myriad changes to brain structure, brain-region connectivity, and brain energy consumption, though many of these changes are only temporary, a study led by researchers at Weill Cornell Medicine has found.

Women become more susceptible to hypertension as they approach menopause, and now a preclinical study led by researchers at Weill Cornell Medicine’s Feil Family Brain and Mind Research Institute suggests that this “perimenopausal” hypertension may be driven by declines in estrogen signaling in a brain region called the hypothalamus—and may be preventable with estrogen-like treatments.