Anesthesiology

A new study unveils a precise picture of how an ion channel found in most mammalian cells regulates its own function with a “ball-and-chain” channel-plugging mechanism. The findings could lead to new drugs that target these channels to treat disorders such as epilepsy and hypertension.

Dr. Jim Castellanos, an instructor in anesthesiology, has been selected as a 2024 Hanna H. Gray Fellow by the Howard Hughes Medical Institute.

Many individuals seeking asylum in the United States show increased stress and pain symptoms that are associated with indications of cardiovascular disease, according to Weill Cornell Medicine researchers.

The general anesthetic propofol may hold the keys to developing new treatment strategies for epilepsy and other neurological disorders, according to a study led by researchers at Weill Cornell Medicine and Linköping University in Sweden.

Researchers at Weill Cornell Medicine have developed a powerful, new technique to generate “movies” of changing protein structures at speeds of up to 50 frames per second.

The molecular workings of a family of important but hard-to-study proteins called CLCs have been illuminated as never before in a study led by researchers at Weill Cornell Medicine.

Dr. Alessio Accardi, professor of physiology and biophysics in anesthesiology at Weill Cornell Medicine, has been awarded a five-year, $2.7 million grant by the National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health (NIH), for fundamental research on cell membrane proteins that have critical roles in biology and are involved in numerous human diseases.

Anesthesiologist and global health expert Dr. Gunisha Kaur and her research team recently won a prestigious National Academy of Medicine (NAM) Catalyst Prize.

Researchers at Weill Cornell Medicine and RMIT University in Australia have discovered that ion channels called BK channels have unique openings in their sides, which drug molecules may be able to access.

A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a study led by researchers at Weill Cornell Medicine.

A non-opioid designer molecule for treating chronic neuropathic pain by calming hyperactive pain-sensing neurons in the peripheral nervous system has had promising results in a preclinical study.

Recent uncertainties regarding the legal status of the Deferred Action for Childhood Arrivals (DACA) program underscore the urgency for policymakers to reassess long-standing restrictions on government-sponsored healthcare subsidies for all immigrants.

Weill Cornell Medicine faculty members were honored with awards for their exemplary achievements in medical research, education and care May 17-18 during Weill Cornell Medicine’s commencement activities.

Two highly similar molecules with essential, but often contrasting, signaling roles in most life forms exert their distinct effects through subtle differences in their bindings to their signaling partners.

The mechanism by which fat-related molecules called lipids regulate pacemaker ion channel proteins, which help control the heart rhythm, has been revealed in a study from researchers at Weill Cornell Medicine.

Dr. Gunisha Kaur, an assistant professor of anesthesiology at Weill Cornell Medicine and medical director of the Weill Cornell Center for Human Rights, has been selected as an Emerging Leaders in Health and Medicine (ELHM) Scholar by the National Academy of Medicine.

Six Weill Cornell Medicine postdoctoral associates, instructors and junior faculty seeking to pursue independent research careers have received 2022 JumpStart Career Development awards.

A three-year, million-dollar grant from the W.M. Keck Foundation will fund an ambitious project, led by Weill Cornell Medicine, to develop a next-generation, high-speed atomic-force microscope (AFM), capable of capturing the dynamics of proteins in unprecedented detail.

A class of proteins known as TMEM16 scramblases permit rearrangement of lipids in the cell membrane chiefly by...

Using an innovative new imaging technique, researchers at Weill Cornell Medicine have revealed the inner workings of a family of light-sensing molecules in unprecedented detail and speed.