Researchers at Weill Cornell Medicine and RMIT University in Australia have discovered that ion channels called BK channels have unique openings in their sides, which drug molecules may be able to access.
Two highly similar molecules with essential, but often contrasting, signaling roles in most life forms exert their distinct effects through subtle differences in their bindings to their signaling partners.
The mechanism by which fat-related molecules called lipids regulate pacemaker ion channel proteins, which help control the heart rhythm, has been revealed in a study from researchers at Weill Cornell Medicine.
