Dr. Simon Scheuring

Researchers at Weill Cornell Medicine have developed a powerful, new technique to generate “movies” of changing protein structures at speeds of up to 50 frames per second.

A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a study led by researchers at Weill Cornell Medicine.

Two highly similar molecules with essential, but often contrasting, signaling roles in most life forms exert their distinct effects through subtle differences in their bindings to their signaling partners.

A three-year, million-dollar grant from the W.M. Keck Foundation will fund an ambitious project, led by Weill Cornell Medicine, to develop a next-generation, high-speed atomic-force microscope (AFM), capable of capturing the dynamics of proteins in unprecedented detail.

Using an innovative new imaging technique, researchers at Weill Cornell Medicine have revealed the inner workings of a family of light-sensing molecules in unprecedented detail and speed. 

Researchers at Weill Cornell Medicine have shown that they can record the high-speed motions of proteins while correlating their motion to function.

Scientists at Weill Cornell Medicine have developed a computational technique that greatly increases the resolution of atomic force microscopy, a specialized type of microscope that “feels” the atoms at a surface.

Researchers at Weill Cornell Medicine have developed and used an advanced imaging technique to reveal the dynamics of two proteins required for many critical cellular functions, including cell division and neurotransmitter regulation. The findings could inform the development of future treatments for conditions in which these proteins are dysfunctional.

Dr. Simon Scheuring, a professor of physiology and biophysics in anesthesiology at Weill Cornell Medicine has been awarded a prestigious National Institutes of Health Director’s Pioneer Award for a project aimed at solving long-standing mysteries about the structural workings of important proteins.

A team of scientists from Weill Cornell Medicine and The Rockefeller University has illuminated the basic mechanism of Piezo proteins, which function as sensors in the body for mechanical stimuli such as touch, bladder fullness and blood pressure.