Dr. Effie Apostolou

The 45th annual Vincent du Vigneaud Memorial Research Symposium, a student-organized event that has become central to the Weill Cornell Graduate School of Medical Sciences experience, had a record number of 153 abstracts submitted this year, including posters and eight oral presentations.

Temporarily disabling a protein complex that organizes DNA into loops inside the cell’s nucleus drastically disrupted the three-dimensional structure of the genome, but surprisingly most genes continued to function as usual, Weill Cornell Medicine researchers found. 

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During their preparation for this battle, B cells transiently revert to a more flexible, or plastic, stem-cell-like state in the lymph nodes, according to a new preclinical study from Weill Cornell Medicine investigators. 

The way DNA folds inside the nucleus of brain cells may hold the key to understanding a devastating form of brain cancer called glioblastoma, suggests a new preclinical study from Weill Cornell Medicine researchers.

A new study by Weill Cornell Medicine investigators reveals that beyond providing a convenient way to store DNA in a tight space, the 3-dimensional (3D) organization of noncoding gene regulators in chromatin contributes to the control of key cell identity programs in early embryonic development.

Awards, honors, prizes and achievements for the month of April.

Molecular "bookmarks," which allow cells to retain their characteristics during cell division, ensure fast reactivation of critical cell identity genes after cell division, according to investigators at Weill Cornell Medicine.

Scientists at Weill Cornell Medicine have discovered how a key transcription factor protein called KLF4 helps “reprogram” skin cells into stem cells, according to a new study.

Stem cells preserve their identities after cell division by using a series of protein “bookmarks” on their genes,...