A gene linked to autism spectrum disorders plays a critical role in early brain development and may shape the formation of both normal and atypical nerve connections in the brain.
Decreased amounts of a neurotransmitter called GABA, whose main function is to reduce activity in the brain, leads to changes in the number of neurons in the developing brain and alters signaling between them.
A calcium-dependent molecular mechanism discovered in the brain cells of mice by Weill Cornell Medicine investigators may underlie the impaired social interactions and anxiety found in neuropsychiatric disorders — including schizophrenia and autism.