A new, very precise gene-editing tool created by Weill Cornell Medicine investigators will enable scientists to study the impact of these specific genetic changes in preclinical models rather than being limited to more broadly targeted tactics, such as deleting the entire gene.
A new set of laboratory models designed to study variations in one of the most commonly mutated genes in cancer has revealed that each variation has a different effect on the colon and pancreas, according to investigators at Weill Cornell Medicine. The models also provide a new platform for screening potential therapies.
The protein adipsin, which is produced in body fat, helps protect insulin-secreting cells called pancreatic beta cells from destruction in type 2 diabetes, according to a new study by researchers at Weill Cornell Medicine and NewYork-Presbyterian.
New molecules engineered by Weill Cornell Medicine researchers can enable rapid, direct “editing” of genes in a wide range of cell types, creating an array of research and therapeutic possibilities.
Genetic mutations caused by rearranged chromosomes drive the development and growth of certain colorectal cancers, according to new research conducted by Weill Cornell Medicine investigators.
